Department of Medicine /research/taxonomy/term/60/all en Is it allergies? /research/features/allergy-season-concerns-during-pandemic <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p><span style="font-size:20px;">How is COVID-19 making this year more challenging for allergy sufferers?</span></p> <p><strong>Dr. Anne Ellis</strong>: Reduced access to primary care will be an issue for patients who suffer from seasonal allergies. Fortunately, most if not all allergy practices have converted to telemedicine and/or virtual care so people can still get in touch with their treating allergist at this time, and pharmacies remain open.</p> <p><span style="font-size:20px;">How are seasonal allergy symptoms similar and different to COVID-19?</span></p></div></div></div><div class="field field-name-field-story-type field-type-list-text field-label-hidden"><div class="field-items"><div class="field-item even">Confronting COVID-19</div></div></div><div class="field field-name-field-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Tags:&nbsp;</div><div class="field-items"><div class="field-item even" rel="dc:subject"><a href="/research/keyword-tags/covid-19-0" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">COVID-19</a></div><div class="field-item odd" rel="dc:subject"><a href="/research/keyword-tags/coronavirus-0" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Coronavirus</a></div><div class="field-item even" rel="dc:subject"><a href="/research/keyword-tags/allergies-0" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Allergies</a></div><div class="field-item odd" rel="dc:subject"><a href="/research/keyword-tags/symptoms-0" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Symptoms</a></div><div class="field-item even" rel="dc:subject"><a href="/research/keyword-tags/allergy-season-0" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Allergy season</a></div></div></div> Tue, 05 May 2020 02:57:00 +0000 kvd1 3176 at /research Eva Kaufmann /research/researchers/eva-kaufmann-0 <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><h2>Innate Immune Memory in Asthma and the Quest for Targeted Immunotherapies</h2> <p>Dr. Eva Kaufmann’s research explores a new concept in innate immunity, termed "innate immune memory", or "trained immunity". Her lab studies whether allergen exposure induces long-lasting epigenetic changes in hematopoietic stem cells and innate immune cells, such as monocytes. Such epigenetic reprogramming can be a reason why asthmatic individuals experience exacerbations and are more susceptible to severe clinical trajectories of respiratory infections.</p></div></div></div> Thu, 01 Feb 2024 18:53:43 +0000 kvd1 25471 at /research The Tiniest Tree of Life /research/photos/tiniest-tree-life <div class="field field-name-field-photographer-s-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Elahe Alizadeh, PhD</div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded">COVID-19, the second pandemic of the current century, is still an ongoing global health emergency. Its complications and mortality are associated with pneumonia and alterations in the pulmonary vasculature. Acquiring 3D images of vascular trees in animal models provide a useful tool to evaluate the effects of COVID-19 in humans. In our research aimed at finding new drugs for COVID-19 under the supervision of Dr. Stephen Archer, vascular trees of a mouse were pressure perfused to maximal dilation with a radio-opaque material (barium). The heart and lungs were fixed and scanned using VECTor4CT scanner. VECTor4CT is the first tri-modality imaging system equipped with an ultra-high-resolution micro-computed tomography (µCT) scanner at Queen’s University.</div></div></div><div class="field field-name-field-location field-type-text field-label-above"><div class="field-label">Location of photograph:&nbsp;</div><div class="field-items"><div class="field-item even">Queen&#039;s CardioPulmonary Unit (QCPU)</div></div></div><div class="field field-name-field-year-of-entry field-type-list-text field-label-above"><div class="field-label">Submission Year:&nbsp;</div><div class="field-items"><div class="field-item even">2022</div></div></div><div class="field field-name-field-photo field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img typeof="foaf:Image" data-echo="/research/sites/default/files/Alizadeh_2022_2560x.jpg" data-icon="" src="/research/sites/all/modules/contrib/lazyloader/image_placeholder.gif" width="2560" height="2560" alt="[Photo of a 3D image of vascular trees in animal models]" title="The tiniest tree of life" /><noscript><img typeof="foaf:Image" src="/research/sites/default/files/Alizadeh_2022_2560x.jpg" width="2560" height="2560" alt="[Photo of a 3D image of vascular trees in animal models]" title="The tiniest tree of life" /></noscript></div></div></div> Tue, 31 May 2022 14:10:01 +0000 kvd1 25274 at /research Is DNA key to whether you get COVID-19? /research/features/dna-key-whether-you-get-covid-19 <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><div> <p>The strength and health of one’s immune system is one key indicator of susceptibility to contracting pathogens, including the novel coronavirus. However, new evidence that may suggest more men get coronavirus than women has motivated an international hunt for which genes make people especially vulnerable or resistant to COVID-19.</p></div></div></div></div><div class="field field-name-field-story-type field-type-list-text field-label-hidden"><div class="field-items"><div class="field-item even">Confronting COVID-19</div></div></div><div class="field field-name-field-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Tags:&nbsp;</div><div class="field-items"><div class="field-item even" rel="dc:subject"><a href="/research/keyword-tags/covid-19-0" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">COVID-19</a></div><div class="field-item odd" rel="dc:subject"><a href="/research/keyword-tags/coronavirus-0" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Coronavirus</a></div><div class="field-item even" rel="dc:subject"><a href="/research/keyword-tags/dna-0" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">DNA</a></div><div class="field-item odd" rel="dc:subject"><a href="/research/keyword-tags/cancer-0" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Cancer</a></div><div class="field-item even" rel="dc:subject"><a href="/research/keyword-tags/research" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Research</a></div><div class="field-item odd" rel="dc:subject"><a href="/research/keyword-tags/genomes-0" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Genomes</a></div></div></div> Wed, 12 Aug 2020 17:27:27 +0000 kvd1 22600 at /research Conversations Confronting COVID-19: Aging /research/conversations-confronting-covid-19-aging <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>The COVID-19 pandemic has threatened our health and communities, including some of our most vulnerable populations, such as the elderly. Have we failed or succeeded in our duty to safeguard the most vulnerable members of our society? What has the national and global response to the pandemic taught us about our preparedness for such a virus? How will the pandemic influence our long-term strategy for healthy aging? These are some of the important questions we examined during <em>Conversations Confronting COVID-19: Aging</em>, the second session in the virtual event series.</p> </div></div></div><div class="field field-name-field-video-url field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">https://www.youtube.com/watch?v=X6BeqFZzWXs</div></div></div><div class="field field-name-field-video-thumbnail-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img typeof="foaf:Image" src="/research/sites/default/files/styles/video_thumbnail/public/assets/videos/20-0083-Discover-Research-at-Queens-VES-Video-Thumbnail-COVID19-Ageing-1200x774.jpg?itok=3_-_i3UE" width="700" height="450" alt="Discover Research@Queen&#039;s - Virtual Event Series" title="Conversations Confronting COVID-19: Aging" /></div></div></div> Wed, 29 Jul 2020 14:33:56 +0000 kvd1 21859 at /research Watch the Discussion: Conversations Confronting COVID-19: Aging /research/articles/watch-discussion-aging-long-term-care-and-covid-19 <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p><span style="color:#FFFFFF;">.</span></p> </div></div></div><div class="field field-name-field-story-type field-type-list-text field-label-hidden"><div class="field-items"><div class="field-item even">Confronting COVID-19</div></div></div><div class="field field-name-field-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Tags:&nbsp;</div><div class="field-items"><div class="field-item even" rel="dc:subject"><a href="/research/keyword-tags/covid-19-0" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">COVID-19</a></div><div class="field-item odd" rel="dc:subject"><a href="/research/keyword-tags/coronavirus-0" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Coronavirus</a></div><div class="field-item even" rel="dc:subject"><a href="/research/tags/health" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">health</a></div><div class="field-item odd" rel="dc:subject"><a href="/research/keyword-tags/long-term-care-0" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Long-term care</a></div><div class="field-item even" rel="dc:subject"><a href="/research/keyword-tags/aging" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">aging</a></div><div class="field-item odd" rel="dc:subject"><a href="/research/keyword-tags/seniors-0" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Seniors</a></div><div class="field-item even" rel="dc:subject"><a href="/research/keyword-tags/senior-care-0" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Senior Care</a></div><div class="field-item odd" rel="dc:subject"><a href="/research/keyword-tags/canada-health-act-0" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Canada Health Act</a></div><div class="field-item even" rel="dc:subject"><a href="/research/keyword-tags/event-0" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Event</a></div><div class="field-item odd" rel="dc:subject"><a href="/research/keyword-tags/integrated-care-0" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Integrated Care</a></div><div class="field-item even" rel="dc:subject"><a href="/research/keyword-tags/healthcare" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Healthcare</a></div><div class="field-item odd" rel="dc:subject"><a href="/research/keyword-tags/elderly-0" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Elderly</a></div></div></div> Wed, 29 Jul 2020 14:24:33 +0000 kvd1 21858 at /research Critical funding for health research /research/features/critical-funding-health-research <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>Seven Queen’s University researchers are contributing their knowledge in the areas of melanoma, intensive care unit survivors, postoperative pain, diabetes medication, Indigenous public health, and depression thanks to funding from the Canadian Institutes of Health Research.</p> <p>Queen’s received a total of $3.95 million from the Fall 2019 CIHR Project Grant competition, a program that helps advance health-related research. With an eye on collaboration, the competition funds both individuals and groups of researchers at any career stage in all areas of health-related research.</p></div></div></div><div class="field field-name-field-story-type field-type-list-text field-label-hidden"><div class="field-items"><div class="field-item even">Research Funding</div></div></div><div class="field field-name-field-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Tags:&nbsp;</div><div class="field-items"><div class="field-item even" rel="dc:subject"><a href="/research/keyword-tags/funding" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Funding</a></div><div class="field-item odd" rel="dc:subject"><a href="/research/keyword-tags/research" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Research</a></div><div class="field-item even" rel="dc:subject"><a href="/research/tags/health" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">health</a></div><div class="field-item odd" rel="dc:subject"><a href="/research/keyword-tags/health-sciences" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Health Sciences</a></div></div></div> Wed, 12 Feb 2020 15:42:28 +0000 kvd1 2913 at /research Translational Institute of Medicine (TIME) /research/centres-institutes/translational-institute-medicine-time <div class="field field-name-field-distributed-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img data-lazyloader="disabled" typeof="foaf:Image" src="/research/sites/default/files/assets/centres/TIME%20DI.jpg" width="1000" height="667" alt="[fibre optic cable]" /></div></div></div> Sun, 22 Sep 2019 21:25:17 +0000 kvd1 2388 at /research Stephen Archer: Recognition for Leadership in Academic Medicine /research/stephen-archer-recognition-leadership-academic-medicine <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>Dr. Stephen Archer, <a href="/research/mc_administrator/node/55">Canada Research Chair in Mitochondrial Dynamics and Translational Medicine</a>, has been awarded the 2019 Association of Faculties of Medicine of Canada (AFMC) President's Award for Exemplary National Leadership in Academic Medicine.</p> </div></div></div><div class="field field-name-field-video-url field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">https://www.youtube.com/watch?v=AylBCX79xLI</div></div></div><div class="field field-name-field-video-thumbnail-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img typeof="foaf:Image" src="/research/sites/default/files/styles/video_thumbnail/public/assets/videos/Stephen_Archer.jpg?itok=_RVfviuO" width="700" height="450" alt="Stephen Archer sitting in front of bookshelf." title="Stephen Archer" /></div></div></div> Wed, 08 May 2019 20:06:33 +0000 moonr 1932 at /research Mapping Mitochondrial Complex I /research/photos/mapping-mitochondrial-complex-i <div class="field field-name-field-photographer-s-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Zhigang Hong</div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded">Super-resolution confocal microscopy of rat pulmonary artery smooth muscle cells showing a network of mitochondria (green) and the location of mitochondrial Complex I (red). We are investigating differences in Complex I in various cell types as it relates to pulmonary arterial hypertension (PAH). </div></div></div><div class="field field-name-field-year-of-entry field-type-list-text field-label-above"><div class="field-label">Submission Year:&nbsp;</div><div class="field-items"><div class="field-item even">2015-16</div></div></div><div class="field field-name-field-photo field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img typeof="foaf:Image" data-echo="/research/sites/default/files/Hong2015_2560.jpg" data-icon="" src="/research/sites/all/modules/contrib/lazyloader/image_placeholder.gif" width="2560" height="2560" alt="Mapping Mitochondrial Complex I" title="Mapping Mitochondrial Complex I" /><noscript><img typeof="foaf:Image" src="/research/sites/default/files/Hong2015_2560.jpg" width="2560" height="2560" alt="Mapping Mitochondrial Complex I" title="Mapping Mitochondrial Complex I" /></noscript></div></div></div> Fri, 01 Feb 2019 20:08:10 +0000 kvd1 914 at /research Mitochondrial Mysteries /research/photos/mitochondrial-mysteries <div class="field field-name-field-photographer-s-name field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Kimberly Dunham-Snary</div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded">Standard confocal versus super-resolution confocal microscopy of rat pulmonary artery smooth muscle cells. The ‘question mark’ mitochondria seen at the centre of the left image is actually three separate organelles. We are characterizing the mitochondrial network of various cell types and determining how this network is related to sensing changes in oxygen levels. </div></div></div><div class="field field-name-field-year-of-entry field-type-list-text field-label-above"><div class="field-label">Submission Year:&nbsp;</div><div class="field-items"><div class="field-item even">2015-16</div></div></div><div class="field field-name-field-photo field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><img typeof="foaf:Image" data-echo="/research/sites/default/files/Dunham-Snary2015_2560.jpg" data-icon="" src="/research/sites/all/modules/contrib/lazyloader/image_placeholder.gif" width="2560" height="1306" alt="Mitochondrial Mysteries" title="Mitochondrial Mysteries" /><noscript><img typeof="foaf:Image" src="/research/sites/default/files/Dunham-Snary2015_2560.jpg" width="2560" height="1306" alt="Mitochondrial Mysteries" title="Mitochondrial Mysteries" /></noscript></div></div></div> Fri, 01 Feb 2019 19:42:32 +0000 kvd1 911 at /research Stephen Archer /research/researchers/stephen-archer <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><h2>The Secret Lives of Mitochondria</h2> <p>Mitochondria are constantly dividing, fusing, and moving throughout your cells. That mitochondria do more than make energy is a relatively new observation, one that has given rise to the young field of mitochondrial dynamics.</p></div></div></div> Mon, 09 Jul 2018 20:00:53 +0000 vandusen 55 at /research “A Translational Journey”: A Special Panel Discussion about Queen’s CardioPulmonary Unit (QCPU) /research/features/translational-journey-special-panel-discussion-about-queen-s-cardiopulmonary-unit-qcpu <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>Cardiopulmonary diseases are the leading cause of death in Canada. Queen’s CardioPulmonary Unit (QCPU) – an 8,000 square foot translational research facility located in Queen’s Biosciences Complex – officially opened on October 6, 2017. Funded by a $7.7M joint award from the Canada Foundation for Innovation and the Ontario Ministry of Research, Innovation and Science, QCPU research focuses on the development, preclinical testing and commercialization of new therapies for heart, lung, blood and vascular (HLBV) diseases.</p></div></div></div> Mon, 18 Jun 2018 20:52:45 +0000 vandusen 52 at /research